Ironically MEA may have made it possible for us to go back to the milky way without having on of the

Actually, it wouldn't unless they made the Milky Way just as unusual as Andromeda on the way back due to other reasons.

Destroy ending vs other endings means Reapers vs no Reapers. Control and Synthesis don't get rid of them entirely or even at all.

Synthesis would have life forms that were part robot and part life - would people even age or be able to have kids in this state? In this instance, if people don't age, there would be issues of people who were alive when the reapers were dealt with still being around. Wouldn't even need any of the old crew.

Actually, no. Synthesis made everyone green in the galaxy.
And you would have to deal with reapers alive vs reaper corpses / humanity dead vs humanity alive in the other endings. So, it's still complicated. 

I'd rather they make new Mass Effects in a parallel universe where there aren't any reapers to worry about. Make new protagonists, new stories.

Really the only way to do it and still make the ending canon is to use time travel/alternate universe via black hole or alien tech somehow.

We come back before the events of Mass Effect 1

Do we have quarians or no quarians. Was the genophage cured or was it not cured(i.e., krogan or no krogan). Do we have geth or no geth. Reapers or no Reapers. Synthesized or not.

It's never been about the specific characters that existed in the trilogy. It's been about the far reaching implications about several decisions, the result of which create world states that are entirely incompatible with each other.

You'd need to create a plotline that presents equal stakes regardless of whether the reapers don't exist at all, are the watchful guardians of the Milky Way, or are active participants in milky way society. You need to account for the fact that either the geth or the quarians or both could be extinct, or that they could be living together in harmony. You need to account for the fact that the krogan could be extinct, have become a threat to the galaxy again, have entered into a civil war with each other, or have entered a new golden age.

This creates a situation where you're either essentially creating at least two different games entirely while using up vast resources for content that some players will never see, or you minimize these elements to such a degree that the entire choice was moot ant pointless to begin with, or you pick a hard canon and piss everyone off.

All that being said, on a related note, I have a personal theory that Bioware has steathily established that Synthesis is not canon because it's been calculated that the reapers could cross dark space and reach Andromeda in less than half the time it took the initiative to make the jump, so in the Synthesis ending where the Reapers are by all appearances working together with the milky way, sharing their knowledge and technology, and helping everyone grow and advance at an exponential rate, you have this very important question of "how is it the post-war, synthesized milky way races haven't lapped the initiative and shown up first?"

And either of those options would leave behind evidence.

Liara found evidence of the Protheans and had an accurate theory on why they disappeared and they weren't around for 50,000 years. I don't think the evidence of what happened at the end of ME3 would disappear in 1,200 years. And the endings are different enough that there would be evidence that would indicate definitively which ending was chosen.

How? how would shepard be alive 1,200 years later.

There are too many questions that need to answered before they can even go back to the Milky Way.

Are the Quarians still alive? If so do they still needs their suits?
Are the Geth still alive?
Is everyone organic/synthetic like the Reapers?
Did everyone die?
Did Shepard decide to control the reapers?
What about the Krogan and the genophage?
What happened to characters who could possibly be alive when you return like Liara, Wrex, Grunt and EDI? Remember Drack is at least 1,400 years old so it's not hard to believe Grunt and Wrex may still be alive. And EDI could live forever so long as she takes care of her body.

There no way they can answer those without being

We return to the Milk Way only to find:



Wouldn't that be a real kick in the cajones?

Shepard is "alive" in two of the ending. In control, he is more or less the reapers and if you pick refuse he lives.  Yes after 1,200 years Shepard would be dead but his legend wouldn't be seeing that he/she is the biggest hero the Milky Way has ever seen. There would be books about him/her, cities, people, planets and holidays named after them by this point. 

Did I miss something?

Cause everybody dies in refuse. Everybody.

I was confusing it with the red ending my bad 

I would love it if BioWare canonized refuse. Just think of all the fans pining for a return to the Milky Way; the faces they'd get when BioWare tells them they get to go home, but everything they know and love is dead and the galaxy is now home to an entirely different race.

Unfortunately though, that wouldn't work for a number of reasons. For one, it would take thousands of years before another civilization would be at the same techlevel we achieved in the trilogy. In that amount of time (barring contrived plot devices), the milky way races in Andromeda would probably have evolved past the point of singularity. More importantly though, BioWare doesn't have the balls.