Ryder/Draak vs Shepard/Wrex

Unless Drack can kill a thresher maw single handedly, I'm going with Wrex. Alec was a badass N7 before he had SAM, and Shepard is an N7 and a Spectre, so I'm going with Shepard and Wrex.

Shepard has killed Reapers. SAM might be an A.I. but it is a significantly less advanced one than the ones Shepard destroyed, and SAM doesn't come packaged with dreadnought class weapons. Not only would the safe money be on Shepard, but the safe bet would be on Shepard whipping both Ryders simultaneously on his way to a more challenging opponent. 

Drack might take Wrex though. That's like the Krogan Mr. T taking on Krogan Chuck Norris. It's gonna be close, and the universe might just implode from too much concentrated awesome colliding.

If we're being nitpicky, which I personally enjoy being, Shepard's only real reaper kill is the human proto-reaper in the Collector base. Everything else was more death by proxy, since Sovereign was defeated by killing its relatively puny avatar, and the Destroyer on Rannoch was technically shot down by the migrant fleet in orbit. All Shepard really had to do was run from the death ray and lase the target. Everything else was basically techno-zombies, and let's face it - Ryder would be just as adept at killing those things as Shepard was. 

Lol what does that have to do with anything? Shep has killed reapers in very specific situations with a lot of help. It's not as if he just pointed his carnifex at one and took it down.

LOL Ryder wouldn't even get off the ground. Pleaseeee.

So if we want an epic fight we need fight music.

Oh god, I just had the though of Wrex and Drack fighting, you're expecting this awesome, epic, badass fight. Then it's just a slap fight like with Morda and Strux hahaha

The questions was actually Shep/Wrex or Ryder/Drack.  So...

I go Shep/Wrex.  Wrex is probably almost as old as Drack.  At minimum, he's over 700 (half Drack's age, I know) but he may be as old as 1000 - or more.  On top of that, he's a krogan battlemaster.  That means he's a badass biotic.  I'd back Wrex.  As for Shepard, no contest.  That could change given more experience for Ryder but as it currently stands I don't see Ryder as capable of taking on Shepard.

***NEVER SYNTHESIS***

Bioware had to make them stupid just so the galaxy has a chance to defeat the reapers

With the green crap. That's exactly what it is, crap.

I think Wrex would destroy Drack.

As for Shepard vs Ryder. Idunno. Gotta look at both objectively. On one hand Shepard saved the galaxy, but he also did it with the help of everyone else. Shepard also died by the collectors and would have stayed dead if not for again his friends (Liara) and of course because of Cerberus.

Shepard has also been outsmarted many times before, more than once by his clone alone. His clone would have succeeded too, if not for the fact that Shepard had superior friends to his clone.

In-game Shepards biggest feats are fighting the human reaper, and the thresher maw on foot. Though technically, it was more like Shepard versus bug babies while the thresher maw remains at a distance spamming ranged attacks. In terms of fighting big giant things on foot, I think Ryder might take this. He fought a total of 4 architects on foot, without any sort of heavy ordinance weaponry that Sherpard always needed to combat large mechanical beings. Hate the game or love it (I kindahate it) that's a pretty big deal. Then you have SAM, who can essentially download tactical expertise of any form into Ryder's brain.

As for Shepard having EDI. I'm almost 100% positive that SAM is far more advanced than EDI. I'm also not sure Shepard is this ''super cyborg'' the fanbase makes him out to be. In-game he shows himself to be as vunerable to injury as the rest of the human characters. Pretty sure he's just more synthetic than actually robotic. I'd like to think that if Shepard really was in part heavy mechanical, that would make fighting Ryder more dangerous since he could just screw around with his electronic parts rendering him useless. I'm 100% positive that Shepards friends would destroy Ryder's. But in a fight between the two without friends and without the plot armor that comes with the territory of being a protagonist, Ryder might win.

Im kinda assuming they're using the same weapons tho...