Save TWO friends!

I voted for Garrus & Mordin (but just because of the shallow feelings I have for both characters).

I think if I really have to chose because background story/deepness of their own story I would definitely go with:
Kasumi & Zaeed

Both had not so much influence on the Shepard arc overall and lack more presence in the game series in general. I really want to know how they would act confronted with all the andromedan stuff that's waiting for us. They had really interesting personalities and I was a bit sad about how they were handled in ME 3.

Edit: + 2 Ninja points for Kasumi & Zaeed

Are we ignoring their vital contribution to stopping the reapers?

In that case it's a toss-up between Liara, Garrus, Tali, Jack and Kaidan.

If we're talking about how useful they could be in Andromeda... they're still all useful. Guns need calibrating. Ancient civilizations need to be studied, tech geeks of all kinds are necessary. You also need good soldiers. And a robot that doesn't need food sounds good too.

Going by how ME3 unfolded for the characters, I think Kaidan should be someplace more cheerful!

Garrus and mordin particularly Mordin, I think he would really enjoy exploring a new galaxy, so much to learn.... I'm starting to hate all the talking about shepard and ME characters, though, I'm realizing how much I'm going to miss them all I hope they have really good characters in store for us in MEA

Remember the hardon everyone had for Nyreen? Where is it now?

Tali and Kelly

Ashley Williams and David Anderson. The kind of people you will need by your side when attacked by armed-to-the-teeth space harambes from another galaxy

Kaidan & EDI, since I used them a lot during ME3, but ideally I'd bring all of the squaddies

But Mordin is old... he probably would not have gotten a lot of time to explore. But he sure would have liked it, agreed.

Well, we know there'll be Turians, right? So the game is already 100% guaranteed sexy. Don't you worry!

Kaidan and Wrex, my good old squad

I'll miss my bottle shooting batman friend Garrus, because...

Miranda, for dat ass (yes, I am a simple man) and the fact that no matter how much I set out determined to try something different when starting an ME2 run, I always gravitate back to her.

And Wrex, my big grumpy lizard buddy. Seriously, the "Shepard, my friend" greeting in ME2 is one of its best moments.

Everything always gravitates back to Miranda......even the Normandy.

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Not that I could blame it.

i.imgur.com/eRM2Y72.gif