The Khet Home World

Both the Khet and Helius Cluster are from the Reddit leak I believe. The Khet are the presumed bad guys of MEA. I hesitate to say antagonist because that role is usually filled by one individual but it very well could be a Khet individual that fills the role.

As Antibaar said the Helius cluster is probably going to be similar to the clusters we found in the Milky Way in the original three games. My guess is it will be much bigger than than any of the clusters we encountered in the ME Trilogy though. The reddit leak says "The next Mass Effect game takes place in the Helius Cluster (a cluster of 100s of solar systems in the Andromeda Galaxy)………" 

Ah, thanks both for the info. That's more or less what I thought, and honestly I'm a bit disappointed about it, just because I was expecting we'd traverse the entire galaxy like we did in the Milky way. Although, I probably shouldn't be disappointed since less than 1% of the Milky Way was actually explored, so we didn't need to across the galaxy anyway, but still. This also makes sense if there will not be any mass relays.

It's been so long I forgot about the system clusters in ME, so my brain was thinking of galaxy clusters instead, hence my confusion

I wonder what they'll do with the khet. Will they be like the Prothean Empire and we'll be rescuing other species from their oppression? Will they end up being defenders, while we're the invaders? Or will they be more enigmatic like the Reapers?

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My understanding from reading the leaks is that the Khet are a war-like malicious race set on expanding their territory
and moving into the cluster. Their behaviour is taken unkindly by the local indigenous races and us making allies of them
is smart politics.

The Remnants, in their prime, achieved a high level of technology of which both the Khet and Ryder must get to gain the leverage
they need to beat the other. I view the Remnants as the MW's Protheans.

I'm sure we will. In the E3 2015 interview when they announced MEA officially, Mac Walters talked about how future games will have us expand further and further into Andromeda.&

I don't think so, since clusters can only be so big before being classified as something else. The clusters we went to in the Shepard Trilogy had hundreds of stars as we can see. It's just we only visit a few of them. This time it sounds like we'll visit every single one or at least a lot more. 

Also, as an astronomy lover the wording in the leak bugs me. There is no such thing as 100s of solar systems. There is only one solar system, the star system of the star Sol aka our Sun.