If we fight darkspawn again can we fight a brood mother again. Like in DAO.

Broodmother would be an okay battle because it's so different, but yeah, I'm okay with the Blight staying far away. It gets shoehorned in too much.

But yes, more creepy stuff.

Just because red lyrium was a plot reveal doesn't mean it must feature in the next game. There were revelations about golems, but they didn't factor into DA2. Blighted golems...that might be interesting.

I'm not sure what you mean by "resolved the plot." It's resolved: Varric told Bianca about the lyrium because he wanted to know what it was. Bianca did her research and needed help, so she then told Corypheus's skin-puppet, whomever survived Legacy. Varric wanted to find out how the red templars got the lyrium and it was Bianca. 

"Demons, dragons, darkspawn, even the Dread Wolf". Unless this was empty rhetoric in the trailer, it did seem to be promising at least more darkspawn. Of course, Tevinter Nights seem to be building up to us finding something even worse than brood-mothers down in the Deep Roads, as if they weren't bad enough. Also in the Descent Rhen was saying how he thought that fighting darkspawn would be never ending until the ultimate source of them was discovered and dealt with. He was suggesting the alpha brood-mother and that could well be something we end up having to deal with. Also there was this work in progress shot from last year:


If a giant, tainted beating heart doesn't give you the chills, I don't know what will!   Also this bit of the trailer seemed to suggest that we may be encountering red lyrium infused darkspawn.

Is that a heart? It looks more like a column of blighted fungus. Not saying that's better.

Well I don't know about a Titan's heart because it looks like it's on the surface to me (based on the sky and the ruined buildings that don't look like the Sha Brytol/dwarven architecture) and if a titan left underground for the surface it's heart would presumably still be within it and thus the sky would be down and the buildings different. But it's certainly pulsating like it's alive. So it might be something's heart, or something growing inside like a cocoon?

Back in DAO and DAA the darkspawn came from growths that were a bit like that didn't they? It seemed as though broodmothers didn't give birth to live offspring so much as laid eggs inside sacs (at least that is what the Mother did). So I suppose it could just be the updated version of that.