Rage & Charge Inquiry

I use Resilience, Regeneration, Berserker on all my krogans.

For charge I use damage and force/Bastion.

Charge: I use radius because the damage is so pitiful a few extra % don't change much. Charge and shoot or charge and melee. With radius it knocks back a few mooks if you charge into a group. I go radius on most (not all) powers actually although that was more useful in ME3MP than in MEAMP. I also go for recharge speed instead or Bastion. Tried bastion but honestly... keeping the cooldown as low as possible you can pretty much charge all the time so no need for extra protection and if everything fails there is still saving barrier...

Regeneration is all the difference in the world. Especially on the vanguard.

You have 3-4x more health than shields, so being able to regenerate to over 40% doubles the amount of damage you can take between charges if you make a mistake, and they happen. You con't have to fear dying when your shields drop because you have lots of health, and losing it doesn't carry over, unlike other classes where losing half your health early leaves you vulnerable later. 

A Huge factor is that your health can keep regenerating as long as you have shields over top, meaning when you are charging around and the enemies aren't dropping your shields between charges you are constantly regenerating your health for emergencies. The 65% max melee boost is not significant enough on it's own to warrant losing so much durability over the course of a game

Resilience is nice, but far less vital, and the 50% melee it competes with is good for krogan who regenerate shields through other sources, the vanguard makes the best use of it.

However, the key is you have to be in rage mode in order to regen health.
So take Rage tree to Berserker is a must.