Should I wait for additional patches to play?

It did not add the ability to manual save during priority missions. Or at least not the one you start in.

If you'll only play through it once, I'd likely wait to see if they plan on adding any DLC that you may be interested in.

Unless you are hugely invested in everything Mass Effect. I'd hold off for a little while. The game definitely lacks polish at the moment, though I will say, if you're a combat enthusiast, this is arguably the strongest in the entire series. My only major gripe with it is not being able to control your squad anymore. But yeah, if you only plan to play through once. Just wait for a price cut.

I appreciate the feedback guys.

Cassandra N1: I have already purchased the game and even started playing it but put it down after a couple hours after losing about an hour of play time due to getting killed on a priority mission. Shortly thereafter I heard about the 1.05 patch and decided to wait.

I suppose it would be nice to have better character customization options because the generic Ryder is not someone I want to look at for 40 hours+ ...

Has there been any word on a time frame for any additional updates?

Do I still have to hit escape twice to get back to the game from the mission journal?

if you don't encounter any gamebreaking pbug or problem, then go ahead and play

i encountered a gamebreaking bug, so i must wait for the next patch

Games not that broke or anything. Just play.

If you're only going to play it once (and inclined to buy DLC) wait until that's all out.

Otherwise, play it now if you feel like it.

...I mean, I'm probably going to be playing this game off and on for years, but I don't actually like many games that much. So the ones that I do, I tend to keep close. It's not my favorite, but it's pretty entertaining.

I certainly am. When the CC is improved and the price drops I'll be able to play the game, finish it and say "hmm, it didn't give me cancer, 7/10".