Lets all join hands here... what was your "moment" with ME. OT or MEA.

I'm going to have to jump onto the Vigil/Ilos bandwagon. That whole scene was a masterpiece of plot exposition (honestly, Bioware have only equalled it with the final conversation of Dragon Age Inquisition: Trespasser)

Thanks to the OP for starting this - it's a less problematic topic for this forum and its inhabitants

I also started ME2 first back when DA2 was first released and Bioware gave the Deluxe Edition owners ME2 as a gift. I loved just about everything about ME2 including the dramatic opening sequence - what a way to start a game. But the best was the entire sequence of going through the Omega 4 relay and the suicide mission.

In ME3 (with all DLCs) it was the opening leaving earth sequence just reeled me in and had me rivetted until the very end which was equally emotional. It was awesome to see the majestic Normandy arrive for pick-up. It felt like home. Unlike many people, I actually enjoyed the ending although I would have loved to have seen my femShep and Garrus live out their retirement from vid royalties

Awesome games and too many moments to choose from.

Edit: the only moment from Andromeda for me is the wtfbbq braking of the Tempest as it hurtled toward that huge Kett Archon ship

Andromeda wise for me was that great intro. The slowly building music, Clancy Browns epic voice, the shuttles skimming the moon and arriving at the Arks just as the music and the traditional ME wordy bit kicks in - amazing! Then followed by the Hyperion arriving at Heleus with Day 0 Hour 0 at the bottom of the screen. That really made me smile!

Love at first sight.

For me it was from the very beginning. It was a big step up from Jade Empire in every aspect.

I chose the bottom line in the first conversation with Joker and Femshep said, "Great. You pissed the Captain off, and now I'm gonna pay for it". The delivery of the line was very real, not like a cartoon voiceover, and Shepard side-eyed Joker as she left. I noticed the realism of the scene. Then there was the chat with Pressly. Femshep asks, "you think the Alliance brass is holding out on us?". Again the facial expression added to the line to produce a great cinematic effect. By that time (2 minutes in) I was absolutely drawn in. What made it was how alive everything was.

I had not experienced that in games. Alyx Vance from Half Life 2 was closest but still not as good.