Where are you buying the legendary edition?

Genocide comes to mind. Synthesis erased all organic life from existence. It's even a greater crime than what the Reapers were doing because it no longer allows organic life to survive in any form.

Something that looks kind of like the organics still exists but they're not the same. They are something other. This pales in comparison to the deaths of the geth. In Destroy, one species is destroyed, and I'm not convinced that can't be restored minus Reaper tech. They were already evolving without it and there's no reason they had to mimic the behavior of organics.

In Synthesis, it's all gone. Even the geth are no longer what they were. They are forced to behave like the former organics, which has essentially robbed them of being the networked (hive?) beings they were.

I know it was meant to be viewed as a fairy tale ending but to me it's unimaginable horror.

We haven't seen that happen in the game.  EDI was the one and only exclusion.

It's an interesting argument, but I'm not sure that it's legit to equate transfprmation and death.

How about bringing your own thoughts to the table?. You seem to spend all your time watching us discuss and argue, while never giving us anything to chew on in return.

If you turn lead into gold is it still lead? If you turned all lead in existence into gold does lead exist?

The changes may be minimal to ME2 and ME3, but from what I've seen of ME1 it appears that they've put a lot of work in.

They won't listen. You're debating with someone who thinks getting an implant is committing suicide, or patents giving their baby gene therapy murdered their aby because both examples the person isn't the same.

I like to think we get taller, stronger, smarter, and metabolize vitamins and nutrients better to extend our natural lifespans. If I can daydream, then maybe biological healing/self-regeneration. But if we want to get scientific, humanity has likely peaked and probably won't evolve much because "survival of the fittest" isn't law of the land. Advantageous genes are no longer the only genes to pass on. Science, in its aim to provide a better quality of life for all (as it should), keeps defects and other disorders ongoing in the sense that these flawed genes aren't a death sentence like they might've been early on and are allowed to pass on to offspring like color blindness, sickle cell anemia, etc. 
I don't know, I mean didn't Andromeda go to show how genocide can be achieved through transformation- aka the Kett and their exaltation or whatever they call it? I would say when you transform something, it is no longer what it once was. It's ambitions, properties, goals and functions change maybe to the point of countering its original functions or goals. 

Taller you say? Cos I'm only Five foot one.

Nope. I've actually gone straight to confused. Explain yourself please.