The Next Mass Effect...

urgh no reboot or prequels. I would take a sequel to either ME 3 or MEA. In the case of the ME 3 I don't mind them picking a canon ending and going with it. People might complain about it but it would work. And despite what people think of MEA it left unanswered questions as well as a lot of potential for future stories in the new lore they established.

Reboot? No thanks. I don't want a Marvel-like reboot and least of all a prequel with predestined ending like the second trilogy of Star Wars movies.
What they could do:
- If they want to make a sequel to ME3, they have to pick the canon ending - that is, Reapers destroyed and Shepard alive - and go with it.
- Instead, if they want to make a sequel to MEA, they have to fill all the plotholes they left in MEA; it would be better if they'd forget about writing a shitty novel about the Quarian Ark ("Nexus Uprising" is a pile of utter rotten horse manure) and put that story as prologue to MEA2.

I don't see why they couldn't do a sequel to Andromeda. Really the fact that it only took 600 years to travel 2.5 million light years means there isn't anything they can't do. My reasons for why they won't is the game was way to easy. Travel should have been a lot more restrictive, we should have had to build settlements that brought in actual resoures and we shouldn't have pretty much instantly become friends with the second advanced lifeform we meet. To me if the game would have been more of a struggle just to survive it would have had a better foundation for another game. Of course this all assumes that EA even cares about a games story in an RPG which I don't think they do unless they somehow can attach micro-transactions to a single player game.

It's all in jest regardless.

I can't see the pic the poster below your post used but in short no.

I've always like the idea of picking a cannon ending and going with indoctrination theory. Though you still have to choose how the korgan and quarian arcs end. Though I feel a lot less people will be upset at those choices being cannonized.

Not exactly, a reboot would be like if Andromeda never happened, but it did happen, we will just ignore it.
Dragon Age 2 pretty much ignores Ferelden, the Blight, and most of Origins' characters, but it's not a reboot. I guess you just don't know what a reboot is. 

No, actually most of the characters WEREN'T there. Leliana only appears at the ending, and Zevran appears at a side quest (if he survived) and Alistair will briefly appears if he's king. Shale, Wynne, Morrigan, Oghren, Sten, they are all out, they aren't even mentioned. The game pretty much ignores characters and events from the first game. The Blight is only mentioned, but it doesn't have any role on the second game, which is completely different from the first. 

In a reboot, you rewrite characters and timelines, which is not the case. The new Spiderman is a reboot, since he's not the same Spiderman of the other movies. You guys really don't understand what a "reboot" is. 

"In serial fiction, to reboot means to discard all continuity in an established series in order to recreate its characters, timeline and backstory from the beginning."

I told you, you DON'T KNOW what a reboot is.  

Dragon Age 2 ignores neither Ferelden or the Blight.