If there was one major thing you could change about this game, what would it be?

Change the first hour of the game. The opening is the weakest in a trend of already declining intros in Bioware games. Everything feels rushed, the dialogue feels like it's from a different game, and doesn't match the quality of the rest of the game. I would have started the game/tutorial back in the Milky Way, introduce the major players of the Initiative, chat with my twin and establish the relationship with them (same with Dad) and work on building up the Initiative into being this bold new awesome organization full of hope and optimism...then when shit inevitably hits the fan and they all panic or turn bad it has more impact.

I would have removed open-world.

Change the name to 'My little pony's space adventure'

Good games with sequels degrading in quality breeds salty fans.

Watch the consensus within the Last of Us fan base get ripped to shit after TLoU Part II ships or shits.

DID YOU JUST CALL ME AN ASSHOLE??!?
No, but while I kinda agree that the fandom vitreol started one place and has cultivated a sort of meanspirited attitude in general it all started with BioWare not being able to live up to their own standards set by ME1 or ME2. When 2 shipped all the literary fan-people started picking it apart for not really being a game where the story itself was the highlight while other fans came to and other ME1 fans felt they had made Mass Effect way better and then 3 had the "it's 95% perfect" and "The ending is 'fine'" crowd but really it fell to pieces right around the time ME3 shipped and because Andromeda is in as such a sorry state as it is I think a lot of people have just lost their respect for the company.

I don't see financial reasons as a good excuse to not fix a game and it just further causes more issues with a fan base if the dev won't fix something they launched half broke. It's far better they use up their own money to salvage what they can rather than letting the ship sink and let their reputation go along with it.

regardless, I see bioware simply taking their time on fixing the game rather than driopping frequent updates. The wait will be excruciating for some, and it might (will) result in some people not even coming back when it finally is patched. However for me myself, I won't mind, I'll be back to try a 2nd run once DLC and patches come through before making a final judgment on the game(honestly though regardless of how good the DLC/patches are, it's not getting a higher score than 8 as first impression is everything(. I understand some want more patches right off the bat, and I don't disagree with bioware taking their time on making sure patches actually patch things when they come out.

let us have six skill slots instead of three. Start with three and earn the other three. I don't have an A.I. in my head to auto switch profiles.
I have a soldier at level 29 with the main combat skills I want and can actually use maxxed on points and feel trapped without more skills to add to active duty.

I've posted the major things I'd want in previous posts on this thread. But here's a tiny do-able one and is totally just fluff and vanity: Fix the texture on the high-ponytail so that it looks like it has hair strands like the lower ponytail and other hairstyles appears to have. That high ponytail looks like a wig with no texture.

And the ability to change eyes, eyebrows and mouth shapes like we can do on every other game out there (including the OT.)

I would have a system like the first Dragon Age where certain squadmates can leave your ship if you piss them off enough. At one point Drack was so pissed off at me he pretty much threatened to smash my face in and to be honest I should have had the option to either put a slug through his thick fucking skull there and then or have him storm off and leave my team forever.

Instead 5 minutes later he's chatting to me like we're best mates again it's weird.

That video you posted was so spot on for me.  Seriously.  Spot. On.  The tone of the game. I wish I could put into words what I want to say with this much frustration.

Have the game made by a competent developer.

*sigh* They were so "clever" in going their own way in MEA (tossing lore every which way or ignoring it), they could have just done the same in the scenario. End of input from me on this.