Be brave. What change are you making to your usual playthrough?

Am thinking of saving Ash on Virmire for the first time, hoping I might be able to stomach her appearance in ME3.

Will definitely let Miranda die during the Suicide Mission, and do whatever it takes to keep Grunt from returning alive from his heroic sacrifice.

Will also be trying to keep the EMS and Readiness as low as I can, just to hopefully avoid the scene where the Normandy evacuates my wounded squadmates while bum-rushing Harbinger at the end. It's the only part of the Extended cut I can't stand, besides the weird timing between Anderson and Shepard making it to the Citadel. I wanna see Garrus and Javik burn heroically instead of calling in resources to save their sorry hides when every second counts and I should be trying to save the galaxy.

Will probably give the Collector base to the Illusive Man.

Might make FemShepard a blonde if the new character creator can bear it out.

Miiiiiiiight leave David at the Overlord facility. Though it'll be tough.

If everything goes as planned, Ashley, Liara, Tali, EDI and James will be the only surviving squadmates by the end of the trilogy. And I might end up killing Ashley too just to spare myself from having to look at her after she recovers in 3.