If its a new protagonist every game...

Why even leave the Milky Way to begin with?

Why not make destroy cannon and play as a series of Path Finders whos job it is to reclaim and repair Mass Relays a few thousand years after the original trilogy.

Mapping new habitable worlds and previously unexplored systems within the 99% of the milky way that remains unexplored

Recovering lost technology and stored memories (If via Protheans) through beacons.

Sam acts as a bridge between yourself and an otherwise indecipherable precursor language much in the same way only with no need for Sudoku.

Along the way you discover evidence of already established precursor species and find out one of them might not actually be as dead as we thought they were.

And now they want their galaxy back.

You as the inexperienced Pathfinder now have a new mission.

Ok its not the greatest idea.

But if we're going on an epic journey to Andromeda why are we swapping PC in roles that should be reclaimed by them in the next installment?

Why wouldn't you just stick with what was there and be honest about creating a new breed of replaceable errand boys under the authority of an established group.

Why make the Pathfinder out to be a title of substance in the first place?

Anyone here who's p*ssed their favorite character or LI didn't get a seat on the Normandy in ME3, raise your hand.

The sad part is that given the way it worked in ME:A, it would have been the perfect time to let us pick between the different species and pull a DA:O style origins thing.

I raise my hand.

I wanted the greatest chef in the universe, Mr. Rupert Gardner, back on the SR2 in ME3 to make his fabulous dish, calamari gumbo, for my Shepard

From what I gathered from reading about the ME trilogy, they didn't have a solid story arc for the overall series. Hence the Dark Energy theme from one game gets dumped and replaced by something else.

But it's possible BioWare does have a multi-game story arc for Andromeda, but not a trilogy) that they're working on, including DLC. Don't forget we've got the book series as well, with The Lost Ark title coming out in a few months.

We don't know what their plans are - so speculate how you want. But if you're going to speculate, use what we do know to put it into a better perspective. Edmonton has been working for 5 years on a totally new IP to be released next year. Which is why Montreal got the bulk of Andromeda. And if Montreal is hiring (as noted in another post), Montreal is working on something; which could be the next installment of Andromeda or something new.

Firstly I'd like to say that I do not think it's going to be a new protagonist every game despite the new info that each new game is going to be more of a contained story, and I'll tell you why: SAM. SAM's the justification for their new class system where the character is capable of learning all the tricks and switching between profiles on the fly. Now it's entirely possibly they just throw that out the window and continue with no justification for it at all, or they contrive a reason for SAM moving from Ryder to someone else, but I think they'll stick with Ryder for this reason.

Secondly, the reason they left the Milky Way was precisely so they wouldn't have to pick a canon ending for the trilogy. We all know that. We've always known that.

Firstly I'd like to say that I do not think it's going to be a new protagonist every game despite the new info that each new game is going to be more of a contained story, and I'll tell you why: SAM. 

TBH I'd trade any of the ME1 companions except Liara for Kasumi, Samara, Thane, Mordin, or Miranda.

ME2 was the best game in the trilogy, period. It had a sense of cohesion all the others lacked.

I was infinitely pissed to be stuck with the bland bozos in ME3 while my Kasumi got a short cameo and Samara another short one.

All so they could then put James Vega into our team, to add insult to injury.

What's the problem? Stasis pods are a thing in the MEU.

Just another game? Andromeda already put ME on that level.